Dr. Fox is an associate professor of pediatrics at the Perelman School of Medicine at the University of Pennsylvania. She is vice-chair of developmental therapeutics for the Children’s Oncology Group and head of developmental therapeutics in oncology at the Children’s Hospital of Philadelphia.
Advances in the treatment of children with cancer include development of new agents as well as optimization of standard therapies and combination therapies. Dr Fox applies an integrative approach to clinical drug development utilizing animal models, pre-clinical and clinical pharmacology to evaluate new agents and novel trial designs for treatment of childhood cancer.
Dr. Fox has expertise in quantitative clinical and pre-clinical pharmacology, pediatric clinical oncology, and clinical research and trial design including response and toxicity biomarker endpoint development and validation. Her laboratory focus is on the application of pharmacology to in vitro and in vivo experiments of anticancer agents and new methods for pharmacokinetic sampling including microdialysis and volumetric absorptive microsampling to develop quantitative assays for drugs in biological matrices to support clinical trials, particularlyminimum sample volumes and sampling strategies appropriate for children.
Dr. Fox earned her medical degree from Pennsylvania State University and an MS in clinical research from Duke University. She completed her internship and residency in pediatrics at Strong Memorial Hospital at the University of Rochester, a fellowship in pediatric hematology/oncology at the Pediatric Oncology Branch of the National Cancer Institute, and served as a lieutenant commander (LCDR/05) in the Department of Health and Human Services for the U.S. Public Health Service.
