Dr. Simeone is the Laura and Isaac Perlmutter Professor of Surgery and Pathology at New York University (NYU) and director of the Pancreatic Cancer Center. She also serves as associate director for translational research for the Perlmutter Cancer Center at NYU.

An internationally renowned pancreatic surgeon and researcher with a long-standing career focus on the treatment of pancreatic neoplasms, Dr. Simeone has been the recipient of numerous National Institute of Health grants (multiple R01s, U01, P50) investigating the molecular mechanisms driving pancreatic metastasis and the development of novel, more effective therapeutic strategies to treat pancreatic cancer patients. She has been an innovator in the development of therapeutic clinical trials for pancreatic cancer, and along with her team runs a large clinical research program dedicated to developing an early detection blood test for pancreatic cancer. She is currently the national principal investigator for Precision Promise, an exciting new adaptive platform clinical trial consortium focused on next-generation clinical trials for patients with pancreatic cancer.

Dr. Simeone has published more than 186 studies in leading peer-reviewed journals and currently serves as the chair of the scientific and medical advisory board of the Pancreatic Cancer Action Network. She has previously served as president of the Society of University Surgeons and the American Pancreatic Association. She is a member of the Institute of Medicine of the National Academy of Sciences.